Insights
Immune checkpoint inhibitor response and resistance
Variability of response and primary resistance to cancer immune checkpoint inhibition, studied in genetically diverse mouse F1 populations.
Variability of response and primary resistance to cancer immune checkpoint inhibition, studied in genetically diverse mouse F1 populations.
Research uses
Host genetic control of variation in checkpoint-inhibitor response; mapping of response-associated loci; evaluation of DO and CC F1 populations as cancer immunotherapy model systems.