Insights
Spontaneous solid tumors
Spontaneous solid-tumor susceptibility in a genetically diverse mouse population: published surveillance across multiple Collaborative Cross (CC) strains showed broad variation in spontaneous tumor incidence and spectrum, and identified CC036 as a spontaneous gastric-tumour model.
Spontaneous solid-tumor susceptibility in a genetically diverse mouse population: published surveillance across multiple Collaborative Cross (CC) strains showed broad variation in spontaneous tumor incidence and spectrum, and identified CC036 as a spontaneous gastric-tumour model.
Research uses
Discovery of spontaneous models for human tumours; host genetic control of tumour susceptibility; inflammatory gene signatures accompanying tumour development, including the Nfkb1 candidate locus and elevated ISG15 protein in gastric adenocarcinoma; biomarker and survival-association research.