Diseases
动脉粥样硬化模型
About this disease
Disease classification:arterial disorder; arteriosclerosis disorder; cardiovascular disorder; vascular disorder; human disease; disease by body system or component
A disease characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen.
Standard definition source:MONDO:0005311 atherosclerosis · ontology version 2026-10-06
Applicable models (published, verified)
- ApoE⁻⁻ 动脉粥样硬化模型 · ApoE 缺失模型用于高胆固醇血症及动脉粥样硬化病变研究。 · Verified applicability
- Ldlr⁻⁻ 动脉粥样硬化模型 · Ldlr 缺失模型用于膳食相关高胆固醇血症及动脉粥样硬化研究。 · Verified applicability
- ApoE-deficient mouse · ApoE 缺失导致自发高胆固醇血症和主动脉粥样硬化病变,用于斑块形成与进展研究。 · Verified applicability
- ApoE-deficient C57BL/6J mouse · C57BL/6J 背景 ApoE 缺失模型用于饮食加速的主动脉斑块形成与进展研究。 · Verified applicability
- ApoE-deficient C57BL/6 mouse · C57BL/6 背景 ApoE 缺失模型用于主动脉粥样硬化病变形成研究。 · Verified applicability
- LDL receptor-deficient mouse · LDL 受体缺失模型用于 LDL 驱动的高胆固醇血症和饮食诱导动脉粥样硬化研究。 · Verified applicability
- LDL receptor-deficient C57BL/6 mouse · C57BL/6 背景 LDL 受体缺失模型用于致动脉粥样硬化饲料诱导的斑块研究。 · Verified applicability
- LDL receptor-deficient C57BL/6J mouse · C57BL/6J 背景 LDL 受体缺失模型用于 LDL 驱动动脉粥样硬化和降脂干预研究。 · Verified applicability
- Cholesterol-fed New Zealand White rabbit · 胆固醇饲料诱导的新西兰白兔模型用于主动脉脂质病变和泡沫细胞形成研究。 · Verified applicability
- Watanabe heritable hyperlipidemic rabbit · WHHL 兔用于 LDL 受体缺陷导致的家族性高胆固醇血症和晚期主动脉病变研究。 · Verified applicability
- LDL receptor-deficient rabbit · LDL 受体缺失兔用于 LDL 清除障碍驱动的主动脉粥样硬化研究。 · Verified applicability
- Balloon-injured rabbit artery · 球囊损伤兔动脉模型用于内皮损伤后内膜增生和加速性动脉粥样硬化研究。 · Verified applicability
- High-fat diet-fed C57BL/6 mouse · 高脂饲料喂养 C57BL/6 小鼠用于饮食诱导代谢紊乱和早期血管表型研究。 · Verified applicability
- High-fat diet-fed mouse · 高脂饲料喂养小鼠用于饮食诱导高脂血症和血管炎症研究。 · Verified applicability
- PCSK9-AAV hypercholesterolemic mouse · PCSK9-AAV 高胆固醇血症小鼠用于成年动物快速诱导高胆固醇血症和斑块研究。 · Verified applicability
- ApoE3-Leiden mouse · ApoE3-Leiden 小鼠用于 APOE 变体与饮食共同作用下的动脉粥样硬化研究。 · Verified applicability
- ApoE-deficient Fbn1 C1039G+/- mouse · ApoE 缺失联合 Fbn1 C1039G 突变用于斑块不稳定和弹性纤维断裂研究。 · Verified applicability
- Cholesterol-fed rabbit · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- Tandem stenosis (TS) mouse model · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ApoE deficiency with AT1 receptor disruption mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- high-fat diet-fed cynomolgus monkey · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- high-fat diet-fed pig · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- cdkn2a deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- lox-1 deficiency with ldl receptor deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- lox-1 overexpression with apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ovariectomy with cholesterol and heated vegetable oil diet Sprague-Dawley rat · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- cetp deficiency rabbit · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- apoe*3leiden.cetp transgenic hyperlipidemia mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ldl receptor deficiency with human apob-100 transgene mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- abca1 and abcg1 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- atg5 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- PCSK9-AAV hypercholesterolemia C57BL/6 mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- qa-1 d227k point mutation mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- apoe and ccr7 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ldl receptor and ccr7 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ldl receptor deficiency with cxcl1 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- hypomorphic sr-b1 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- sr-b1 and apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- sr-b1 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- mmp-12 deficiency with apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- mmp-3 deficiency with apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- nox5 deletion New Zealand White rabbit · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- pon1 overexpression mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ucp2-deficient bone marrow transplantation mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- endothelial piezo1 deletion with ldl receptor deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- endothelial plxnd1 deletion mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- partial carotid ligation with pcsk9 overexpression C57BL/6 mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- jak2 v617f clonal hematopoiesis mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- streptozotocin-induced diabetes with adipose ucp1 expression pig · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- tet2 clonal hematopoiesis mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ucp1 deficiency with apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- hiv transgene with apoe deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- genetic plaque instability model with inducible angiotensin ii mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- high-fat diet-fed golden Syrian hamster · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- LDL receptor-deficient golden hamster · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- aav-crispr somatic ldlr disruption mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ldl receptor deficiency with loss of apob mrna editing mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- sr-bi and ldl receptor deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- sr-bi deficiency with hypomorphic apoe mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- apoe and par2 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- ldl receptor and par2 deficiency mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- AAV8-PCSK9 with Western-type diet mouse · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- aortic transplantation mouse model · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
- Golden Syrian hamster · 动脉粥样硬化病变及相关血管表型研究。 · Verified applicability
References
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