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Experimental methods

metabolomics by mass spectrometry assay

What this technique is

Category
Omics
Principle
A mass spectrometry assay that identifies and measures metabolites.
Input samples
mouse serum · mouse liver tissue extract
Research questions
Not provided
Output and readout
非靶向质谱给出代谢物谱并按组间多元统计(如 PCA 分离)与差异代谢物判读。
Applicability
用于代谢表型研究的小鼠血清/组织 LC-MS 或 GC-MS 非靶向代谢组学,如膳食与基因型干预的代谢指纹比较。
Limitations
非靶向结果偏重相对定量,绝对定量需标准品;平台、提取与归一化流程不同批次间不直接可比。

Standard concept source:OBI:0003782 · OBI · 2026-05-08

已发布模型

No published relation.

References

  1. metabolomics by mass spectrometry assay (OBI:0003782), OBI 2026-05-08
  2. Untargeted analysis using Agilent 1290 LC coupled to 6545 Q-TOF (PMID:33631374)
  3. GC-MS based metabolite profiling with PCA group separation (PMID:42851331)