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Experimental methods

电子显微成像

What this technique is

Category
Histopathology
Principle
利用电子束探测样品的密度、形状与组成,并在电子显微镜中形成图像。
Input samples
brain tissue · tissue sections
Research questions
Not provided
Output and readout
输出细胞与组织超微结构图像,可用于观察突触、细胞器及神经元结构变化。
Applicability
用于脑组织等样品的超微结构研究,透射电镜可观察超薄切片中的内部结构。
Limitations
超微结构形态不能单独确认分子身份;局部取样的图像不能直接代表整个脑区。

Standard concept source:OBI:0001631 · OBI · 2026-05-08

已发布模型

No published relation.

References

  1. Electron microscopy (OBI:0001631; OBI 2026-05-08)
  2. electron microscopy imaging assay (OBI:0001631), OBI 2026-05-08
  3. Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model. Current Alzheimer Research. 2016
  4. Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer’s disease. Neuroreport. 2017