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abca1/abcg1 knockdown zebrafish (developmental angiogenesis reference)

The English availability of this content could not be established, so the Chinese version is the stable reference. 英文译文可用性待核实,以中文版为准。 查看中文内容 · Chinese version

Cholesterol transporter Abca1/Abcg1-deficient embryos display dysregulated, extensive angiogenesis.

Model identity

Model name
abca1/abcg1 knockdown zebrafish (developmental angiogenesis reference)
Species
zebrafish
Genotype / zygosity
abca1 and abcg1 knockdown

Biological characteristics

Research questions
Whether cholesterol transporter loss affects developmental angiogenesis.
Limitations
Embryonic knockdown readout concerns developmental vessel growth; it is a mechanism reference rather than a disease-model entry for metabolic syndrome endpoints.

References

  1. Zebrafish lipoprotein and angiogenesis research review (PMID:24095954)
  2. ARRIVE 2.0 guidelines