stalactite (stl) mtp mutant zebrafish (lipid-angiogenesis mechanism reference)
The stl mutation in the gene encoding Mtp, which is involved in VLDL assembly in the yolk, dysregulates angiogenesis.
Model identity
- Model name
- stalactite (stl) mtp mutant zebrafish (lipid-angiogenesis mechanism reference)
- Species
- zebrafish
- Genotype / zygosity
- mtp stl loss-of-function
- Allele
- stalactite (stl)
Biological characteristics
- Research questions
- What the stl mutant reveals about Mtp and apoB lipoprotein effects on angiogenesis.
- Limitations
- A developmental lipoprotein-assembly mechanism reference; not a model of adult dyslipidemia endpoints.