2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine（PhIP）（文献参考）

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Composition: PhIP（2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine），食源性致癌物
Use information: 用于建立PhIP诱导的啮齿类结直肠癌模型。PhIP经肝脏CYP1A2代谢为N2-Hydroxy-PhIP，后者经磺化或乙酰化后形成活性酯，进而形成DNA加合物；文献推荐该模型诱导Apc突变肿瘤，而不伴P53或Kras突变。

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Reagent：2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine（PhIP）（文献参考）

Stable id：reagent-526（Internal inquiry reference (site id; not a merchant catalog or manufacturer SKU)）

Specification: unknown (not verified)