Spontaneously Hypertensive Rat (SHR)
Arguably the most comprehensively studied model of genetic hypertension, with predisposition to dyslipidemia as a metabolic-syndrome trait.
模型身份
- 模型名称
- Spontaneously Hypertensive Rat (SHR)
- 物种
- rat
- 品系
- SHR
生物学特性
- 适用研究问题
- Which rat strain models genetic hypertension with dyslipidemia as components of the metabolic syndrome.
- 模型局限
- Selected for blood-pressure genetics; obesity/diabetes traits are not intrinsic, so it covers hypertension and dyslipidemia components rather than full metabolic syndrome.