abca1/abcg1 knockdown zebrafish (developmental angiogenesis reference)
Cholesterol transporter Abca1/Abcg1-deficient embryos display dysregulated, extensive angiogenesis.
模型身份
- 模型名称
- abca1/abcg1 knockdown zebrafish (developmental angiogenesis reference)
- 物种
- zebrafish
- 基因型／合子状态
- abca1 and abcg1 knockdown
生物学特性
- 适用研究问题
- Whether cholesterol transporter loss affects developmental angiogenesis.
- 模型局限
- Embryonic knockdown readout concerns developmental vessel growth; it is a mechanism reference rather than a disease-model entry for metabolic syndrome endpoints.