抗tau抗体

参考文献

1. Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology. PMID: 27113998 (2016). · PMID: 27113998
2. In vitro generation of tau aggregates conformationally distinct from parent tau seeds of Alzheimer's brain. PMID: 30422056 (2018). · PMID: 30422056
3. Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction. PMID: 31822518 (2019). · PMID: 31822518
4. Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids. PMID: 32632204 (2020). · PMID: 32632204
5. MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. PMID: 32632205 (2020). · PMID: 32632205
6. Tau phosphorylation by glycogen synthase kinase 3beta modulates enzyme acetylcholinesterase expression. PMID: 32955735 (2020). · PMID: 32955735
7. The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome. PMID: 33258073 (2020). · PMID: 33258073
8. Targeting histone K4 trimethylation for treatment of cognitive and synaptic deficits in mouse models of Alzheimer's disease. PMID: 33298440 (2020). · PMID: 33298440
9. Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology. PMID: 34668266 (2021). · PMID: 34668266
10. Novelty-like activation of locus coeruleus protects against deleterious human pretangle tau effects while stress-inducing activation worsens its effects. PMID: 35005208 (2021). · PMID: 35005208
11. Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. PMID: 35867714 (2022). · PMID: 35867714
12. Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection. PMID: 36130084 (2022). · PMID: 36130084
13. RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation. PMID: 36357715 (2022). · PMID: 36357715
14. Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells. PMID: 36399251 (2022). · PMID: 36399251
15. Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease. PMID: 36576642 (2022). · PMID: 36576642
16. APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation. PMID: 37791598 (2023). · PMID: 37791598
17. The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology. PMID: 37849026 (2023). · PMID: 37849026
18. Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients. PMID: 38041855 (2023). · PMID: 38041855
19. Cell redistribution of G quadruplex-structured DNA is associated with morphological changes of nuclei and nucleoli in neurons during tau pathology progression. PMID: 38649330 (2024). · PMID: 38649330
20. Long-term exposure to excessive norepinephrine in the brain induces tau aggregation, neuronal death, and cognitive deficits in early tau transgenic mice. PMID: 39592915 (2024). · PMID: 39592915
21. Inhibition of Bone Morphogenetic Protein Signaling Prevents Tau Pathology in iPSC Derived Neurons and PS19 Mice. PMID: 39644182 (2024). · PMID: 39644182
22. Lactylation of tau in human Alzheimer's disease brains. PMID: 39740133 (2024). · PMID: 39740133
23. Tau-targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy. PMID: 41344379 (2025). · PMID: 41344379
24. Blautia coccoides-derived metabolite trimethylamine-N-oxide exacerbates Alzheimer's disease progression via targeting HIF1alpha signaling. PMID: 41459734 (2025). · PMID: 41459734

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