Insights
Autoimmunity, inflammation and idiosyncratic drug toxicity
Domain entry for immune-mediated inflammation and idiosyncratic drug toxicity, covering two literature directions: CC spontaneous-colitis line CC011/Unc as an intestinal inflammation reference, and the CC multi-strain panel for tolvaptan idiosyncratic liver-injury susceptibility.
Domain entry for immune-mediated inflammation and idiosyncratic drug toxicity, covering two literature directions: CC spontaneous-colitis line CC011/Unc as an intestinal inflammation reference, and the CC multi-strain panel for tolvaptan idiosyncratic liver-injury susceptibility.
Research uses
Spontaneous-model reference for intestinal immune inflammation and IBD mechanisms; strain-level susceptibility and risk stratification of idiosyncratic drug-induced liver injury; candidate genes and serum biomarkers of DILI susceptibility.
Related models
References
https://pubmed.ncbi.nlm.nih.gov/24487921/