high-cholesterol diet-fed zebrafish
Feeding a high-cholesterol diet increases the proportion of VLDL and LDL fractions in zebrafish plasma and results in a lipoprotein profile closely resembling that of human plasma.
模型身份
- 模型名称
- high-cholesterol diet-fed zebrafish
- 物种
- zebrafish
生物学特性
- 适用研究问题
- Whether high-cholesterol feeding produces a zebrafish model relevant to early atherosclerosis and hypercholesterolemia.
- 模型局限
- Diet-induced hypercholesterolemia in a small organism; lesion progression is vascular-change and lipid-profile based rather than full atheromatous plaque disease.