bilateral common carotid artery occlusion rat (strain not reported)
Bilateral irreversible occlusion of the common carotid arteries produces subtotal forebrain ischemia with pronounced pathobiochemical disturbance and oxidative stress.
模型身份
- 模型名称
- bilateral common carotid artery occlusion rat (strain not reported)
- 物种
- rat
生物学特性
- 表型出现阶段
- Injury develops over hours to days; chronic changes require longer follow-up.
- 适用研究问题
- Subtotal cerebral ischemia; oxidative stress; chronic hypoperfusion.
- 模型局限
- The strain is not reported. BCCAO does not reproduce a territorial MCA infarct or penumbra, so focal TTC infarct measurement is not a valid primary readout.