two-vessel occlusion rat (strain not reported)
Two-vessel occlusion produces global forebrain ischemia in lightly anesthetized rats and is used for delayed neuronal death studies.
模型身份
- 模型名称
- two-vessel occlusion rat (strain not reported)
- 物种
- rat
生物学特性
- 表型出现阶段
- Global ischemic injury and delayed neuronal death develop over hours to days.
- 适用研究问题
- Global cerebral ischemia; delayed neuronal death; hippocampal vulnerability.
- 模型局限
- This is a global ischemia model, not focal stroke, and does not have a penumbra. Strain is not reported.