two-vessel occlusion global cerebral ischemia Mongolian gerbil
Mongolian gerbils lack a complete cerebral Circle of Willis and develop global cerebral ischemia after bilateral common carotid artery occlusion.
模型身份
- 模型名称
- two-vessel occlusion global cerebral ischemia Mongolian gerbil
- 物种
- Mongolian gerbil
生物学特性
- 表型出现阶段
- Global ischemic injury develops over hours to days; hippocampal injury is a characteristic endpoint.
- 适用研究问题
- Global cerebral ischemia; hippocampal vulnerability; delayed neuronal death.
- 模型局限
- This is a global ischemia model, not focal stroke, and is specific to the gerbil Circle of Willis anatomy.