跳至主要内容

unilateral common carotid artery occlusion Mongolian gerbil

Irreversible unilateral common carotid artery occlusion in gerbils reproduces persistent global brain ischemia because of their incomplete Circle of Willis.

模型身份

模型名称
unilateral common carotid artery occlusion Mongolian gerbil
物种
Mongolian gerbil

生物学特性

表型出现阶段
Global ischemic injury develops over hours to days.
适用研究问题
Persistent global cerebral ischemia; hippocampal injury.
模型局限
This is a global ischemia model, not focal stroke; gerbil anatomy is required and strain/source vary.

参考文献

  1. Belenichev I, Bukhtiyarova N, Ryzhenko V, Makyeyeva L, Morozova O, Oksenych V, Kamyshnyi O. Methodological Approaches to Experimental Evaluation of Neuroprotective Action of Potential Drugs.. International journal of molecular sciences. 2024. PMID:39408802.
  2. ARRIVE 2.0 官方规范