Lyon Hypertensive (LH/Mav) rat
Selectively bred for spontaneous hypertension from a small founder population of six Sprague-Dawley rats; carries additional metabolic-syndrome trait risk as an inbred selected strain.
模型身份
- 模型名称
- Lyon Hypertensive (LH/Mav) rat
- 物种
- rat
- 品系
- LH/Mav
生物学特性
- 适用研究问题
- Which inbred selection rat strains model metabolic syndrome traits beyond blood pressure.
- 模型局限
- A narrow-founder selected line; metabolic traits accompany hypertension rather than defining the strain, and generalization to outbred metabolic syndrome is limited.