alpha cell-specific ZnT8 knockout mouse
Alpha cell-selective ZnT8 null mice displayed unaltered glucose tolerance.
模型身份
- 模型名称
- alpha cell-specific ZnT8 knockout mouse
- 物种
- mouse
- 基因型／合子状态
- ZnT8 deletion restricted to alpha cells
生物学特性
- 适用研究问题
- Whether alpha cell ZnT8 deletion affects glucose tolerance and paracrine islet function.
- 模型局限
- The negative glucose-tolerance result means this line is used for islet paracrine mechanism comparison rather than as a disease model.