高脂饲料 (60% kcal fat)

组成

60% 热量来自脂肪的高脂纯化饲料，用于诱导肥胖、胰岛素抵抗与代谢综合征。

使用说明

科研实验；规格与库存请向店铺确认。

已发布方案版本

• 小鼠口服葡萄糖耐量试验（OGTT） · Fasting · 高脂饮食模型维持饲料 按研究设计 · 60% kcal fat 高脂饲料用于 HFD 组；对照组使用标准饲料

  来源版本：protocols.io · vv1 · Nancy Smith; Mourad Ferdaoussi; Haopeng Lin; Patrick E Macdonald · This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

  葡萄糖耐量试验
  NOD mouse · 已验证适用 · 糖尿病模型（NOD mice with slow insulitis development were compared with BDC2.5/NOD mice to identify paths associated with early insulitis.；已验证适用） · 糖尿病肾病 (DN)（NOD 小鼠：自身免疫 1 型糖尿病伴肾小球 PAS 病变（综述推荐）；已验证适用）
  db/db mouse · 已验证适用 · 糖尿病模型（db/db mice were compared with db/+ controls and with the STZ-HFD model.；已验证适用） · 代谢疾病（db/db 小鼠（背景未报到实体粒度）：Lepr db/db 瘦素受体功能缺陷，用于遗传性肥胖与 2 型糖尿病研究。；已验证适用） · 2型糖尿病 (T2D)（Which metabolic and renal abnormalities develop in db/db mice; kidney tissue, urine and serum from db/db mice；已验证适用） · 糖尿病肾病 (DN)（db/db 小鼠（背景按各研究记载）：白蛋白尿与肾小管线粒体损伤读出；已验证适用）
  high-fat diet plus low-dose streptozotocin-induced type 2 diabetes C57BL/6J mouse · 已验证适用 · 糖尿病模型（Glucose tolerance and insulin sensitivity assessed by GTT and ITT；已验证适用） · 代谢疾病（高脂饮食联合低剂量链脲佐菌素诱导的 2 型糖尿病模型，用于糖代谢、胰岛素抵抗及代谢并发症研究。；已验证适用） · 2型糖尿病 (T2D)（How chromatin accessibility, transcript isoforms and RNA modifications are remodeled in diabetic cardiomyopathy.; Whether HFD/STZ mice develop diabetic cardiomyopathy with transcriptional and epigenetic remodeling.；已验证适用）
  high-fat diet plus streptozotocin-induced type 2 diabetes C57BL/6 mouse · 已验证适用 · 糖尿病模型（Mice received 4-6 weeks of 60% kcal fat diet then one 100 mg/kg STZ dose and 12 further weeks of HFD.；已验证适用） · 2型糖尿病 (T2D)（Does the STZ-HFD model produce more intervertebral disc inflammation and degeneration than db/db?; Intervertebral discs from male C57BL/6 mice, 12 weeks old at start, n=13 STZ-HFD and n=7 vehicle controls；已验证适用） · 糖尿病肾病 (DN)（HFD+STZ C57BL/6 小鼠：肾损伤与线粒体动力学终点；已验证适用）
  high-fat diet-induced obesity and diabetes C57BL/6J mouse · 已验证适用 · 糖尿病模型（HFD-fed mice developed glucose intolerance, insulin resistance, fasting hyperglycaemia and dyslipidaemia, and noise exposure accelerated these changes.；已验证适用） · 2型糖尿病 (T2D)（Does liver-directed AAV-BMP7 reverse diet-induced obesity and insulin resistance?; Male C57BL/6J mice fed chow or HFD for 6 weeks from 2 months of age, then followed about 6 months；已验证适用）
  streptozotocin-induced diabetes C57BL/6 mouse · 已验证适用 · 糖尿病模型（High-dose streptozotocin-induced insulin-deficient diabetic mice were used to study diabetic wound healing and the PNS mechanism; this is not a type 2 diabetes model.；已验证适用） · 糖尿病肾病 (DN)（STZ 糖尿病 C57BL/6 小鼠：HMGB1/系膜与小管间质终点；已验证适用）