Lyon Hypertensive (LH/Mav) rat
Selectively bred for spontaneous hypertension from a small founder population of six Sprague-Dawley rats; carries additional metabolic-syndrome trait risk as an inbred selected strain.
Model identity
- Model name
- Lyon Hypertensive (LH/Mav) rat
- Species
- rat
- Strain
- LH/Mav
Biological characteristics
- Research questions
- Which inbred selection rat strains model metabolic syndrome traits beyond blood pressure.
- Limitations
- A narrow-founder selected line; metabolic traits accompany hypertension rather than defining the strain, and generalization to outbred metabolic syndrome is limited.