WOKW rat (Wistar Ottawa Karlsburg W)
A spontaneous polygenic model of the metabolic syndrome showing obesity, hypertension, dyslipidemia, glucose intolerance and hyperinsulinemia.
Outcome measures
血糖浓度读数。
Experimental animals
Experimental procedures
**Measurement of Blood Glucose ** **Measurement of Blood Glucose ** Blood samples were collected from the tail vein for the determination of blood glucose levels using Accutrend Plus test strips and meter (Roche).
Model identity
- Model name
- WOKW rat (Wistar Ottawa Karlsburg W)
- Species
- rat
- Strain
- WOKW
Biological characteristics
- Research questions
- Which spontaneous polygenic rat strains model the full metabolic syndrome.
- Limitations
- Polygenic inheritance; individual trait severity varies across colonies, and the RT1u haplotype background must be controlled when comparing substrains.
Experimental methods
Experimental protocols
Reagents and materials
- Accutrend Plus 血糖试纸与读数仪
血糖检测耗材与读数平台
- Accutrend Plus 血糖试纸与读数仪
血糖检测耗材与读数平台
References
- Rat Models of Metabolic Syndrome. Methods in Molecular Biology 2019 (PMID:31228162)
- protocols.io · vv2 · Michael Hill · This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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