high-fat diet-fed Wistar rat
Wistar rats fed a purified high-fat diet develop features of metabolic syndrome: DIO groups show significantly increased fasting plasma glucose, plasma insulin and triglycerides versus controls.
Outcome measures
血糖浓度读数。
Experimental animals
Experimental procedures
**Measurement of Blood Glucose ** **Measurement of Blood Glucose ** Blood samples were collected from the tail vein for the determination of blood glucose levels using Accutrend Plus test strips and meter (Roche).
Model identity
- Model name
- high-fat diet-fed Wistar rat
- Species
- rat
- Strain
- Wistar
Biological characteristics
- Research questions
- Whether a high-fat diet induces metabolic syndrome features in Wistar rats, including glycemic, insulin and lipid readouts.
- Limitations
- Outbred diet-induced model; plasma adiponectin and leptin responses differ between high-fat and high-fat-fructose subgroups, so hormonal readouts are diet-composition dependent.
Experimental methods
Experimental protocols
Reagents and materials
- Accutrend Plus 血糖试纸与读数仪
血糖检测耗材与读数平台
- Accutrend Plus 血糖试纸与读数仪
血糖检测耗材与读数平台
References
- High-fat diet induces metabolic syndrome features in Wistar rats (PMID:30322196)
- Rat Models of Metabolic Syndrome. Methods in Molecular Biology 2019 (PMID:31228162)
- protocols.io · vv2 · Michael Hill · This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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