high carbohydrate-high fat diet-induced rat model (cafeteria diet)

Cafeteria-style hypercaloric feeding in rats produces obesity, dyslipidemia, hyperinsulinemia, glucose intolerance, insulin resistance, hyperglycemia and inflammation.

Outcome measures

血糖浓度读数。

Experimental animals

大鼠尾静脉血糖测定

Tissue: blood

Experimental procedures

**Measurement of Blood Glucose ** **Measurement of Blood Glucose ** Blood samples were collected from the tail vein for the determination of blood glucose levels using Accutrend Plus test strips and meter (Roche).

Model identity

Model name: high carbohydrate-high fat diet-induced rat model (cafeteria diet)
Species: rat

Biological characteristics

Phenotype stage: Hyperphagia and weight gain begin within days; full metabolic-syndrome picture develops over 8-16 weeks depending on diet mix.
Research questions: Palatable-diet overconsumption, hypothalamic leptin resistance, and the most complete metabolic-syndrome spectrum among dietary rat models.
Limitations: Cafeteria compositions vary widely between laboratories, making cross-study comparison difficult; intake is voluntary so caloric load is inconsistent across animals.

Experimental methods

葡萄糖测定

Experimental protocols

大鼠尾静脉血糖测定
Measure rat tail-vein blood glucose using Roche Accutrend Plus test strips and meter.

Reagents and materials

Accutrend Plus 血糖试纸与读数仪
血糖检测耗材与读数平台

References

Model consultation